The expanded amelogenin polyproline region preferentially binds to apatite versus carbonate and promotes apatite crystal elongation
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منابع مشابه
The expanded amelogenin polyproline region preferentially binds to apatite versus carbonate and promotes apatite crystal elongation
The transition from invertebrate calcium carbonate-based calcite and aragonite exo- and endoskeletons to the calcium phosphate-based vertebrate backbones and jaws composed of microscopic hydroxyapatite crystals is one of the great revolutions in the evolution of terrestrial organisms. To identify potential factors that might have played a role in such a transition, three key domains of the vert...
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Bone apatite contains carbonate and is therefore not pure hydroxyapatite. We have successfully developed sintered carbonate apatite (CA) with a concentration of carbonate of 6 weight% and have evaluated its osteoconductive and bioresorption characteristics. Cylindrical porous sintered CA and sintered hydroxyapatite (HA) measuring 4 x 4 mm with a porosity of 20% were implanted into surgically-cr...
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Introduction The ideal bone substitute is a material that can be completely replaced by newly formed bone. Hydroxyapatite has been widely used as a bone substitute because of its excellent biocompatibility and osteoconductive ability. The clinical application of hydroxyapatite may be limited, because it does not seem to be resorbed appreciably. In order to improve these disadvantages, we have s...
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In contrast to extensive studies on hydroxyapatite thin films, very little has been reported on the thin films of carbonated apatite (dahllite). In this report, we describe the synthesis and characterization of a highly crystalline dahllite thin film assembled via a biomimetic pathway. A free-standing continuous precursor film of carbonated calcium phosphate in an amorphous phase was first prep...
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ژورنال
عنوان ژورنال: Frontiers in Physiology
سال: 2014
ISSN: 1664-042X
DOI: 10.3389/fphys.2014.00430